Purinergic receptors in the endocrine and exocrine pancreas

Interaction between the Exocrine and Endocrine Pancreas

Pancreatic duct cells express Na-dependent glucose transporter, SGLT1 and Na-independent glucose transporters, GLUT1, GLUT2, and GLUT8. We examined transepithelial glucose transport by pancreatic duct. Interlobular ducts were isolated from rat pancreas. During overnight culture both ends of the duct segments sealed spontaneously. The lumen of the sealed duct was micropunctured and the luminal f...

Mixed exocrine-endocrine tumors of the pancreas.

Neoplasms of the pancreas usually show either ductal, acinar, or endocrine differentiation. Mixed exocrine-endocrine pancreatic neoplasms, in which the endocrine component is significant and comprises one-third to one-half of the tumor tissue, are rare. Truly mixed tumors have to be distinguished from exocrine neoplasms with scattered endocrine cells. In ductal adenocarcinomas, the scattered en...

Mixed exocrine-endocrine tumor of the pancreas.

CONTEXT Neoplasms of the pancreas usually show ductal, acinar or endocrine differentiation. Tumors with mixed exocrine and endocrine components are unusual. We herein describe a case of a mixed ductal-endocrine tumor. CASE REPORT A 65-year-old woman was referred to our department with a diagnosis of carcinoma of the tail of the pancreas. The patient had a short history of upper abdominal pain...

Pancreas: An Endocrine and Exocrine Organ

Pancreas: An Endocrine and Exocrine Organ